It will be related to a setting that you have changed. 

What are the states of the Dtr/Rts buttons on the serial monitor?

Please provide the information requested in the yellow box near the top of the page.

A leonardo upload has existed for many years. There are many settings that can be changed in Visual Micro that will cause a difference such as optimization, rts, board menu properties and other properties. 

The arduino ide doesn't provide most of them but it does provide the board menu properties. Reviewing your configuration might show that some of your defaults have been changed but will certainly show other valuable information. That's why we always ask for it.

If you have not already provided it then please follow the guide in yellow at the top of the page. In your case also enable vMicro>Uploader>verbose. Then build and upload after resetting the board. 

It's important to provide the information so that we can help you.

Thanks for the upload output. We also need the info requested in the yellow box at the top of the page it shows the version of visual micro ans your build settings. Its important. 

Yes we extrended the leonardo upload a few months ago to cater for the updated spec.

You have not enabled this

Enabled vMicro > Compiler > Show Build Properties

Please enable it and click Build>rebuild then email the output

Thanks for the info. We will test it next week and produce any required fix.

Normally the usb driver install for each platform is prompted to install when you install the board package.

If I recall the point of the leonardo is that it is usb capable and therefore does not need the a sperate mcu on the board to handle usb. Therefore the discussion of alternative/chinese drivers for cloned boards is not applicable.

You are using the standard arduino leonardo board selection so you can probably install the original arduino leonardo usb driver that the arduino cc avr board package installs.

You can find the driver for manual install "dpinst-amd64.exe", below the location of where your board package is installed. probably something like this...

C:\Users\[YOUR NAME]\AppData\Local\arduino15\packages\arduino\hardware\avr\1.8.6\drivers

Have you installed the arduino driver package i said to install?

Also send your output again because it shows the usb driver info. You have changed things since the last one.

Thanks for the clarification that usb drivers are working. Dont change anything, we will look at it and resolve issues next few days.

Also confirm if a simple test project such as blink uploads okay in vs2022 or not. 

Thanks